This application study describes a method to quantify the unconfined yield strength of moderately consolidated powders using Stable Micro System’s TA.XTPlus. This method was presented by Polizzi, Yuan and Hancock in their poster “Direct Measurement of the Unconfined Yield Strength of Moderately Compressed Pharmaceutical Powders” at the AAPS Annual Meeting in 2011. Unconfined Yield Strength is a measurement of the force required to cause unsupported material to shear. It is a very useful metric to evaluate powders’ flow behaviors and thus assist companies in understanding the propensities of powders to experience caking, arching, rat-holes, erratic flow, uneven distribution of active ingredients, etc. It is important to know the UYS of powders to understand how they need to be stored, transported and metered throughout any production process.

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