Liquid Soft Gels

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puncture strength

Abstract

We tested the puncture strength of four brands of liquid filled soft gel capsules with the TA.XTPlus Texture Analyzer using a TA-51 Wire Holder, which held a 1 mm diameter punch probe. The capsules tested included Vicks (P&G’s) DayQuil LiquiCaps, Alka-Seltzer Plus (Bayer’s/R.P.Scherer) Liqui-Gels, Sudafed (Borroughs Wellcome) Multi-Symptom Cold & Cough, and Payless Drug Store’s Day Time Liquid Caps. All samples were nondrowsy cold and flu formulations which were selected due to highly similar active and inactive ingredients, geometries and soft gel capsule sizes.