Application Studies / Syringeability with a TA-3

Syringeability with a TA-3

syringe on texture analyzer

Industry:

Pharmaceutical

Attributes measured:

compression

extrusion

Background

The ease with which injectable pharmaceuticals flow out a syringe and through a needle determines how easily the preparation can be administered, impacts patient comfort during injection and affects how the material is received when deposited under the skin. This “syringeability” can easily be measured by pushing down on a filled syringe piston with the TA.XTPlus Texture Analyzer and recording its resistance to compression. In the following example, the force required to express three liquids from a 3 cc disposable syringe out a 22 gauge needle was determined. The syringe was filled with 3 cc of fluid and, with the needle pointing straight down, the piston was pushed a distance of 35 mm at a test speed of 1.0 mm/sec using a TA-3 1” diameter cylinder probe.

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